- Review Article
- Haploidentical hematopoietic stem cell transplantation in children and adolescents with acquired severe aplastic anemia
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Ho Joon Im, Kyung-Nam Koh, Jong Jin Seo
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Clin Exp Pediatr. 2015;58(6):199-205. Published online June 22, 2015
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Severe aplastic anemia (SAA) is a life-threatening disorder for which allogeneic hematopoietic stem cell transplantation (HSCT) is the current available curative treatment. HSCT from matched sibling donors (MSDs) is the preferred therapy for children with acquired SAA. For patients who lack MSDs, immunosuppressive therapy (IST) is widely accepted as a first-line treatment before considering HCT from an unrelated donor (URD).... |
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- Original Article
- Clinical features of infantile hepatic hemangioendothelioma
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Eun Hee Kim, Kyung Nam Koh, Meerim Park, Bo Eun Kim, Ho Joon Im, Jong Jin Seo
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Clin Exp Pediatr. 2011;54(6):260-266. Published online June 30, 2011
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Purpose Infantile hepatic hemangioendothelioma (IHHE) is the most common type of hepatic vascular tumor in infancy. We conducted this study to review our clinical experience of patients with IHHE and to suggest management strategies. MethodsWe retrospectively analyzed the medical records of 23 IHHE patients (10 males, 13 females) treated at the Asan Medical Center between 1996 and 2009. ResultsMedian age at diagnosis was... |
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- Case Report
- A case of anemia caused by combined vitamin B12 and iron deficiency manifesting as short stature and delayed puberty
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Seung Min Song, Keun Wook Bae, Hoi-Soo Yoon, Ho Joon Im, Jong-Jin Seo
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Clin Exp Pediatr. 2010;53(5):661-665. Published online May 31, 2010
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Anemia caused by vitamin B12 deficiency resulting from inadequate dietary intake is rare in children in the modern era because of improvements in nutritional status. However, such anemia can be caused by decreased ingestion or impaired absorption and/or utilization of vitamin B12. We report the case of an 18-year-old man with short stature, prepubertal sexual maturation, exertional dyspnea, and severe... |
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- Original Article
- Ototoxicity in children receiving cisplatin chemotherapy
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Hee Jin Jang, Hyung Rae Cho, Jae Hee Lee, Kun Yuk Bae, Jong Jin Seo, Hyung Nam Moon, Ho Joon Im
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Clin Exp Pediatr. 2010;53(2):210-214. Published online February 15, 2010
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Purpose : Cisplatin is highly effective for the treatment of solid tumors in children. However, the clinical use of cisplatin is limited by its ototoxicity. The aim of this study was to evaluate the ototoxicity in children treated with cisplatin.
Methods : We performed a single institution retrospective analysis of pediatric oncology patients who received cisplatin therapy between January 2001 and... |
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- Prognostic significance of minimal residual disease detected by a simplified flow cytometric assay during remission induction chemotherapy in children with acute lymphoblastic leukemia
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Kyung Nam Koh, Meerim Park, Bo Eun Kim, Ho Joon Im, Chan-Jeoung Park, Seongsoo Jang, Hyun Sook Chi, Jong Jin Seo
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Clin Exp Pediatr. 2010;53(11):957-964. Published online November 30, 2010
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Purpose Our study attempted to determine the prognostic significance of minimal residual disease (MRD) detected by a simplified flow cytometric assay during induction chemotherapy in children with B-cell acute lymphoblastic leukemia (B-ALL). MethodsA total of 98 patients were newly diagnosed with precursor B-ALL from June 2004 to December 2008 at the Asan Medical Center (Seoul, Korea). Of those, 37 were eligible for... |
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- Outcome and risk factors of pediatric hemato-oncology patients admitted
in pediatric intensive care unit
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Bo Eun Kim, Eun Ju Ha, Keun Wook Bae, Seongguk Kim, Ho Joon Im, Jong Jin Seo, Seong Jong Park
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Clin Exp Pediatr. 2009;52(10):1153-1160. Published online October 15, 2009
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Purpose : To evaluate the risk factors for mortality and prognostic factors in pediatric hemato-oncology patients admitted to the pediatric intensive care unit (PICU).
Methods : We retrospectively reviewed the medical records of pediatric hemato-oncology patients admitted at the PICU of the Asan Medical Center between September 2005 and July 2008. Patients admitted at the PICU for perioperative or terminal... |
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- Case Report
- A Case of Nasal T/NK-cell Lymphoma
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Jung Bok Lee, In-sang Jeon, Ho Joon Im, Young Ha Oh, Ji Hye Kim
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Clin Exp Pediatr. 2003;46(12):1266-1270. Published online December 15, 2003
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The advance of the immunobiology clarifies the nature of non-Hodgkin's lymphoma(NHL). In addition the proceed in the immunophenotyping renders the classification of NHL. According to the Revised European American Lymphoma(REAL) classification, classified by the etiologic factors, molecular biological characteristics, immunophenotype, cytogenetics and histologic feature, nasal T/NK-cell lymphoma(=angiocentric lymphoma) belongs to the category of peripheral T-cell and natural killer cell lymphoma.... |
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- Original Article
- Analysis of Treatment in Pediatric Germ Cell Tumor
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Young Dai Kim, Su Hyun Kim, Ki Joong Kim, Ho Joon Im, Hahng Lee
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Clin Exp Pediatr. 2002;45(1):103-108. Published online January 15, 2002
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Purpose : This report is an analysis of our experience with surgery, multi-agent chemotherapy
and radiotherapy, in pediatric germ cell tumors(GCTs).
Methods : This report included all children(age < 15 years) who were registered between November
1985 and May 2001 with a histologically confirmed diagnosis of GCT and received surgery,
chemotherapy and radiotherapy. Retrospective analysis of the medical records of these patients
was performed. In... |
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- Case Report
- Two Cases of Infantile Hemangioendothelioma of the Liver in Neonates
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Soo Jin Han, Soo Shin Cho, Gwang Hoon Lee, Ho Joon Im, Seong Ho Kim, Gil Hyun Kim, Hak Soo Lee
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Clin Exp Pediatr. 2001;44(12):1469-1474. Published online December 15, 2001
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Infantile hemangioendothelioma(IHE) of the liver is a rare benign vascular tumor that presents most commonly in infants before the age of 6 months. IHE presents as abdominal mass, cutaneous hemangiomas, unexplained jaundice, bleeding disorders, or congestive heart failure. Death often results from congestive heart failure despite appropriate treatment with digoxin and diuretics. IHE also is associated with Kasabach-Merritt syndrome, anemia,... |
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- Original Article
- Comparison of Brainstem Auditory Evoked Response in
Normal Infants, Male and Female, Right and Left Ear
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Soo Jin Han, Soo Shin Cho, Kang Ho Cho, EeIl Ryoo, Gwang Hoon Lee, Ho Joon Im, Kye Hwan Seol, Gil Hyun Kim, Hak Soo Lee
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Clin Exp Pediatr. 2001;44(11):1243-1248. Published online November 15, 2001
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Purpose : Brainstem auditory evoked response(BAER) is used as screening test for hearing disorders, damages of the central nervous system and congenital anomalies. We studied the difference values according to gender and stimulation sites in normal full-term infants.
Methods : We performed BAER in 38 male and 28 female normal full-term infants, delivered in the Gil Medical Center, Gachen Medical School,... |
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- Treatment Outcomes in Children with High-Risk Acute Lymphoblastic Leukemia
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Kyu Chang Park, Ho Joon Im, Sang Yun Ahn, Hahng Lee
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Clin Exp Pediatr. 1999;42(3):383-389. Published online March 15, 1999
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Purpose : The survival rate of those with acute lymphoblastic leukemia(ALL) has been affected by several prognostic factors and previous reports show that a 4-year event-free survival(EFS) for high-risk(HR) group(Age≥10 years and/or WBC≥50,000/mm3 at diagnosis) was approximately 64%. We analyzed treatment outcomes and risk factors in HR-ALL.
Methods : Medical records of 27 patients with HR-ALL diagnosed between May, 1985 and... |
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- A Clinical Study of Survival Rate and Prognostic Factors in Advanced Neurobalstoma in Children
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Seung Yang, Ho Joon Im, Nam Su Kim, Hahng Lee
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Clin Exp Pediatr. 1998;41(5):684-694. Published online May 15, 1998
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Purpose : Despite the use of improved therapeutic modalities, long-term survival remains poor in patients in stage Ⅲ or Ⅳ of neurobalstoma and for over 1 year olds at diagnosis. We evaluated the long-term survival rate and related prognostic factors in advanced neuroblastoma.
Methods : Twenty-nine children diagnosed with stage Ⅲ or Ⅳ neuroblastoma after 1 year of age, between May... |
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- Study on the Frequency of Right Bundle Branch Block After Surgical Closure of Ventricular Septal Defect
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Ho Joon Im, Jin Nyoung Park, Nam Su Kim, Jeh Hoon Shin, In Joon Seol, Soo Ji Moon
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Clin Exp Pediatr. 1993;36(1):88-93. Published online January 15, 1993
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The purpose of this study is to evaluate the ventricular conduction abnormalities, especially RNNN, observed electrocardiographically after sugical closure of VSD.
The present study population consists of 92 patients with VSD who were surgically corrected at the Hanyang University Hospital during 6 years period from Jan. 1985 to Dec. 1990. We reviewed their clinical records including surgical notes and EKG findings... |
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- Case Report
- A Case of Video Game Epilepsy
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Jin Nyoung Park, Ho Joon Im, Sung Lae Park, Jeh Hoon Shin, In Joon Seol, Soo Ji Moon
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Clin Exp Pediatr. 1992;35(12):1756-1761. Published online December 15, 1992
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Video game epilepsy is a photic induced sensory evoked seizure, and the seizure occurs only following a specific program of video game.
We experienced a case of video game epilepsy in a 12 year old boy who presented with seizure during video game, and showed photoconvulsive response on photic stimulated EEG. |
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- Original Article
- A clinical study on twin.
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Ho Joon Im, Sang Yoon Ahn, In Joon Seol, Soo Jee Moon, Hahng Lee
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Clin Exp Pediatr. 1991;34(5):621-628. Published online May 31, 1991
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Among the total of 17,991 newborns delivered at Hanyang University Howpital from January 1980
to December 1989, a clinical study was performed on 277 twin pregnancies.
The results of the study were as follows:
1) The incidence of twins was 1:64.9.
2) The average male-female sex ratio of twins was 1:1.1, total same sex pairs rate was 79.4%
(male-male & female-female) and different sex rate was 20.6%.
3) The... |
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- A case of interstitial pulmonary fibrosis.
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Hak Won Kim, Ho Joon Im, In Joon Seol, Ha Baik Lee, Hahng Lee, Seok Chol Jeon, Moon Hyang Park
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Clin Exp Pediatr. 1991;34(1):107-114. Published online January 31, 1991
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Interstitial pulmonary fibrosis is a rare, diffuse lug disease which has a tendency to destroy the lung
architectures by consequent healing with progressively severe fibrosis.
We report with a brief review of literature, one case of a 7-year old female with the typical pictures
of interstitial pulmonary fibrosis, histologically on open lung biopsy, and clinically presenting with
chronic respiratory difficulty but without definite symptoms... |
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